クラウンエーテルを含む混合リン脂質ベシクルの錯形成に関する界面電気化学的研究
1992 年 41 巻 2 号 p. 142-148
詳細
1992 年 41 巻 2 号 p. 142-148
Mixed vesicles including phosphatidylcholine (PC), phosphatidyl serine (PS) and amphoteric crown ether compound (C18-crown-6) with different component fractions were prepared and their ion-complexing phenomena examined by measuring their electrophoretic mobilities in different salt solutions. The crown ether compounds retained their selectively ion-complexing ability for some special cations (K+ and Ba2+) even on the vesicle surfaces. The zeta-potentials of the mixed vesicles of PC+PS+crown were determined extensively by fraction of the PS component and variation in metal cations in aqueous solution. That is, this parameter shifted remarkably in a negative direction with increase in the PS-fraction only in salt solutions containing K+ or Ba2+. No shifting of zeta-potentials could be detected in the case of (i) PC+PS vesicles without crown ether or, (ii) salt solutions that did not complex with the crown ether (Li+ or Ca2+).
