The Japanese Journal of Pharmacology
Online ISSN : 1347-3506
Print ISSN : 0021-5198
ISSN-L : 0021-5198
TOPICAL ACTIVITY OF BENDAZAC ON EXPERIMENTAL BURNS
R. LISCIANIP. SCORZA BARCELLONAB. SILVESTRINI
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1971 年 21 巻 1 号 p. 69-73

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Bendazac or 1-benzyl-indazole 3-oxyacetic acid is a topical antinflammatory drug which in previous experiments was shown to preferentially inhibit inflammatory processes progressing towards necrosis (1). This activity has been temptatively related to a prevention of protein denaturation (2-4).
The aim of these experiments was to study effects of bendazac and hydrocortisone on heat-induced burns and on acetic acid-induced erythema. Two differently formulated creams have been investigated, in an attempt to find out the most suitable one for topical uses.
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