PMSによる家兎の過排卵誘起におけるEstrogen併用の効果
1968 年 14 巻 2 号 p. 43-46
詳細
1968 年 14 巻 2 号 p. 43-46
Effect of estrogen administration on ovulation, recovery of ova and fertilization in rabbits treated with PMS were studied. Thirty-five mature Japanese white does, each weighing about 3 kg were used. The method of treatment in this experiment were shown in Fig. 1. The hormone used were PMS (Serotropin; Teikoku Hormone Mfg. Co. Ltd. Tokyo), HCG (Synahorin; ibid) and estradiol benzoate (Ovahormone Benzoate; ibid). The results obtained are as follows.
In rabbits accompanied with 0.05, 0.1, 0.15, 0.2 and 0.5 mg of estradiol at the last PMS treatment, the average number of ovulation points was 22.0, 37.4, 37.4, 30.0 and 37.6, respectively, and the percentage of ova recovered was 81.8, 55.6, 71.7, 81.3 and 72.9%, respectively, and the percentage of ova fertilized was 88.9, 78.0, 78.4, 76.5 and 91.9%, respectively.
In rabbits mated at the 48 hr after last PMS, and accompanied with 0.1 mg of estradiol at the last PMS or at the 24 hr after last PMS, the average number of ovulation points was 36.0 and 34.2 and the percentage of ova recovered was 88.3 and 82.5%, and the percentage of ova fertilized was 99.3 and 93.6%, respectively.
These results suggested that superovulation in the rabbit is able to produce by gonadotropin (PMS) accompanied with 0.1 mg or more of estradiol administration.
