日本レーザー医学会誌
Online ISSN : 1881-1639
Print ISSN : 0288-6200
ISSN-L : 0288-6200
光化学療法の問題点
-protoporphyrin の腫瘍集積性とレーザー光の組織透過性に関する検討-
樫村 博正福富 久之川北 勲蔡 承熹中原 朗三田村 圭二武藤 弘大菅 俊明
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ジャーナル フリー

1985 年 5 巻 3 号 p. 79-84

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抄録
Tissue localizing ability of protoporphyrin in mice have been described. Protoporphyrin was analized by means of Dresel' s method. The amount of protoporphyrin which localized in the transplanted tumor tissue of mice at various times following i v. injection (20mg/kg) was higher than in the skin, music or intestinal tissue but was less than in the liver or spleen tissue. These results show that tissue distribution of protoporphyrin was similar to that of Hp D. Furthermore, comparison of transmission between 514.5nm and 630nm light have been studied by PRT and spectrophotometer. The results suggested that 630nm light transmission was prior to that of 514.5nm light.
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