表面弾性波を利用した細胞剥離による細胞接着性の定量的比較

抄録

Cells adhere to a substrate and/or other cells to proliferate, meaning cell adhesion is one of the most important mechanical properties of cells to be quantitatively measured. In this study, we developed a method to quantitatively measure the difference in cell adhesion by utilizing the peeling phenomenon observed when cells are irradiated to surface acoustic waves. By using the proposed method, we demonstrate that the adhesion force of myoblasts cultured on a surface acoustic wave device can be regulated by changing the PBS immersion time before detachment. The detachment force becomes able to be quantitatively compared by the proposed method.