ロボティクス・メカトロニクス講演会講演概要集
Online ISSN : 2424-3124
セッションID: 2P2-O02
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引張刺激に対する iPS 由来 3 次元心筋組織の拍動特性
上杉 薫塚本 佳也日浦 綾美赤木 隆美宮川 繁澤 芳樹明石 満森島 圭祐
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In this report, we measured pulsatile properties of three dimensional (3D) iPS-cardiac tissues by using micro vacuum chuck (MVC). The 3D iPS-cardiac tissue was connected to force transducer by MVC in little change of initial length and minimally stress concentration. By using MVC, we successfully applied tensile stimulation to 3D iPS cardiac tissue and measured pulsation force. It was observed that the pulsation force became larger with the increase of strain. Additionally, the pulsation force did not decrease with incubation time. This indicates that the 3D iPS cardiac tissue was not deterioration with time. The pulsation frequency of partially tissues also became large with the increase of strain and this property was increased when incubation time became over 14 days. It means that 3D iPS cardiac tissues kept maturation after 14 days.

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