電界誘起気泡デバイスを用いた網膜静脈閉塞症治療のための研究

抄録

Retinal vein occlusion is a disease that causes vision disorder due to occlusion of the retinal vein which is one kind of micro-vascular spreading to the fundus. Most of the current treatments are aimed at suppressing symptoms caused by vascular occlusion. In this study, we focused on the impact pressure of micro-jet generated by the collapse of the electrical-induced bubbles. This pressure can be worked as local and minimally invasive physical stimuli from the outside of the blood vessel to resolve the vascular occlusion itself. Capacitance measurements were conducted to sense the approach of the device to the target. In addition, we conducted experiments to eliminate thrombus in vascular occlusion model in vitro and in vivo to establish a new treatment method for retinal vein occlusion targeting vascular occlusion.