2003 年 53 巻 3 号 p. 299-302
A 78-year-old man consulted our hospital after experiencing nipple discharge although there was no pain or itching. A firm tumor with irregular surface was palpable at the right nipple. No swelling of axillary lymph nodes was noted. The levels of tumor markers, carcino-embrionic antigen and carbohydrate antigen 15-3, were within a normal range. Mammograms showed a tumor shadow with spicula and microcalcification. Computed tomography (CT) of the right breast indicated no invasion of the tumor into the right major pectoralis muscle. Chest and abdominal CT and systemic bone X-ray showed no evidence of distant metastasis. Diagnosis following biopsy was ductal carcinoma of the breast. A simple mastectomy was performed in November 1997. The cut-section was composed of a white-color solid mass. The values of estrogen and progesterone receptors were 110 fmol/mg and 270 fmol/mg, respectively. As an adjuvant therapy, tamoxifen at a dose of 20 mg/day was administered for 2 years and 10 months after the operation. There have been no recurrence or metastasis of breast cancer for 5 years after the operation. (Kitakanto Med J 2003 ; 53 : 299302)
