1996 年 49 巻 p. 152-153
We investigated the relationship between neutrophil infiltration and trace minerals with Helicobacter pylori. The subject of investigation are 10 cases which reacted to the Hp proved by positive 4 cases by negative. We studied the number of neutrophilia in gastric lamina propria mucosae per an unit area and quantity of zinc and copper in same mucosa.
Hp positive gastric mucosa showed more marked neutrophil infiltration compared to Hp negative mucosa (p<0.05) . On the other hand, Hp positive gastric mucosa was more likely to be associated with low concentration of zinc and copper than Hp negative mucosa (p<0.05) . The abovementioned data disclosed the fact that the degree of neutrophil infiltration altered in reverse proportion to the amount of trace minerals in Hp positive gastric mucosa (r zn=0.65133, r cu=0.67195) .
We confirmed the correlation between the neutrophil infiltration and the quantity of zinc and copper, in gastric mucosa infiltrated with Helicobacter pylori.