A 45-year-old man with ulcer in the residual stomach was treated with anti-Helicobacter pylori (HP) therapy. After the patients had been treated intermittently because of his gastrointestinal ulcer for 6 years, his duodenal ulcer was perforated and he was treated with wide resection of the stomach followed by Billroth I reconstruction on November 1994. He visited our hospital on July 1995 because of epigastralgia, and the endoscopic examination revealed the ulceration in his residual stomach at H1 stage.
He was diagnosed as positive HP-infection by rapid urease test, pathological finding, and bacterial culture using by selected Schirow's medium. After the patient was treated with H2 receptor anagonist (famotidine) for 4 weeks, and the ulceration improved at S1 stage, lansoprazole, amoxicillin and clarithromycin were applied for the eradication of HP. The eradication of HP infection was confirmed by 13C urea breath test, as well as rapid urease test, pathology and culture before and after the treatment. Ulceration in the residual stomach improved to S2 stage after eradication of HP with a recovery of gastrointestinal symptom of the patient.