抄録
The patient was a 15-year-old, junior high school boy. His family and past history were non-contributory. He had an onset of lymphadenopathies at cervical region around September, 1964, and was admitted to hospital on October 29th because of enlargement of lymphnodes at axillar and inguinal regions.
Physical examination on admission showed no sign of anemia, tonsil hypertrophy, hepatosplenomegaly, and several to more than ten, pea-to child fist sized lymphnodes were noticed at each region mentioned above. White blood cell count was 12500. Peripheral blood pictures showed 73.5% of lymphoid cell with nuclei and lymphatic leukemia was suspected from bone marrow smear pathological findings of lymphnodes. However, phase contrast microscopy showed cytoplasmic protrusions to each direction, but did not reveal the movement of “hand-miller-type”. Electron microscopy proved cells different from lymphocytes, but fibrous structure was not so marked in the silver impregnation stain of lymphnodes. From these findings the diagnosis of leukemic reticulum cell sarcoma was given. Temporary regressions of lymphnodes and hepatosplenomegaly were noted by endoxan and radiotherapy, although prednisolone was not responded.