毒性研究にちなむPenicillium islandicumの型別分類について

抄録

In 1950, H. Tsunoda (a member of the group the writer belongs to) published the conclusion that the damage source of yellowed rice was found to be a kind of mold nomenclated as Penicillium islandicum Sopp and also reported that the damaged rice artificially cultivated caused cirrhosis hepatitis to rats used as the test animal of per os administration. Since the report was published, the mold has been used as a tool of experiment on hepatitis widely in medical field.
In continueing the concerning studies, the writer has found the existence of several strain in the mold above described and also noticed that the qualitative and quantitative differences, or strength of toxicity of the pigments produced showed a possibility to be an index for their taxonomic relationships.
To make the attempt convincible, the description on the further study to have provedthe evidence that each strain was characteristically the origin of each specific type of hepatitis, is necessary. Because of space limitation, only the summarized conclusions are presented.
1) The pigment produced is to be an index for the taxonomic relationships of strain of Penicillium islandicum Sopp of which morphological classification having been found to be difficult.
2) The strains are classified under the three types: Flavoskyrin type, Islandicin type and Erythroskyrin type.
Classificational type Produced pigment
3) Examining the coloration of colony reverse, Flavoskyrin type gives orange colored fungus, Islandicin type, deep reddish orange, and Erythroskyrin type, black orange coloration.