抄録
The relation between antimicrobial action and copolymerization of oxidized fish oils was studied.
The fact that the reversal action of nitrogenous substance on antimicrobial action of oxidized calamary oil methyl ester has a direct bearing on copolymer formation from them (Table 1), suggested that the antimicrobial action of oxidized fish oils was responsible for copolymerization of oxidized fish oils with protein. Both antimicrobial action and copolymerization of oxidized oils were accelerated by the primary oxidative product of oils, hydroperoxide (Table 2, 3), but hydroperoxide content in oxidized fish oils was not a limiting factor in the antimicrobial action. The most important reaction leading to copolymer formation from oxidized fish oils and protein seemed to involve a built-up film formation reaction which consists of a protein-lipid linkage and a lipid-lipid linkage.
Copolymerization of the antimicrobial fish oils with protein of the microbe cell wall would change the permeability of the cell wall. This effect can brought about either by blocking the entry of various nutrients into the cell or the diffusion of metabolites into the external environment, or by inactivating an enzymic system.
