1992 年 58 巻 1 号 p. 63-67
Paralytic toxicity was detected in the gastropod mollusk Niotha clathrata from Taiwan. The toxicity scores of specimens collected from Chiating, Kaohsiung Prefecture and Tungkang, Pingtung Prefecture in August 1989 were 13.1±5.9 and 7.9±4.0 (mean±S. E.) MU, respectively. The highest score was 107MU at Chiating and 40MU at Tungkang. The toxicity of specimens was not only detected in the digestive gland, but also detected in the other edible parts. The toxin was partially purified from toxic specimens of N. clathrata by ultrafiltration using a Diflo YM-2 membrane, followed by chromatography on a Bio-Gel P-2 column. Analyses by TLC, electrophoresis, and HPLC showed that the fraction I toxin of N. clathrata contained tetrodotoxin (TTX), and that the fraction II toxin was different from TTX and remained as an unidentified toxin.