Effect of Denatured Plasma on Peripheral Circulation

Abstract

The effect of administration of a longterm perfused plasma on the peripheral circulation was studied by means of the equilibration curve of intravenously injected ⁵¹Cr-tagged red cells. The equilibration of ⁵¹Cr-tagged red cells was prolonged when a long-term perfused plasma was injected. LMD and ATP were effective in preventing the disturbance of circulation caused by denatured plasma; insulin and NEM were less effective; and cortisone showed a significantly favorable effect. Sequestration of blood in various organs could not be comfirmed in rabbits to which denatured plasma was injected.