HLA Antigens in Cancer of the Gallbladder

Abstract

YAMAMOTO, M., HAGA, M., TAKAGI, S., ENDOH, K., ITO, S., YOSHIDA, K., KATO, K. and AKAM, S. HLA Antigens in Cancer of the Gallbladder. Tohoku J. Exp. Med., 1990, 161(1), 67-71 - Thirty one patients with gallbladder cancer (GBC) and 32 healthy controls were typed using antisera against 12 HLA-A, 31 HLA-B, 7 HLA-C and 13 HLA-DR antigens. The DR4 frequency of 61.3% (19/31) in GBC was significantly different from that of 28.1% (9/32) in the control (p=0. 00794 by Fisher's exact test). The relative risk and the etiologic fraction were 4.0 and 0.46, respectively.