The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Studies on Sialic Acid (Neuraminic Acid) in Cerebrospinal Fluid
Part 3: Methodology of Determination by Bial's Reaction
Akira MukaiTatsunori Ejima
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1962 Volume 77 Issue 3 Pages 223-229

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Abstract
We examined Bial's reaction applied for estimation. of sialic acid in the cerebrospinal fluid samples, consisting in whole and protein-free cerebrospinal fluid and the protein in it. We concluded it was difficult to estimate sialic acid in the samples of whole and protein-free cerebrospinal fluids by this reaction.
We suppose the free or non-protein-bound sialic acid is inconstant and a large part of the sialic acid in the cerebrospinal fluid is in the protein-bound form.
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© Tohoku University Medical Press
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