Studies on the Optimum Condition of Coronary Artery Perfusion under Hypothermia

Abstract

Optimum conditions for coronary flow under hypothermia were experimentally investigated on dogs. The control of coronary perfusion by flow rate alone was occasionally accompanied by undesirable side-effects, and adequate perfusion pressure was found to be important in sustaining optimum coronary flow. The most favorable results were obtained at perfusion pressures of 90mmHg at 30&C, 50mmHg at 25°C and 40mmHg at 20°C.