抄録
The frequency of neuropathy in 155 diabetic patients in Kyushu, Japan was found to be 43 percent. Duration of diabetes and in particular the status of control and the presence of microangiopathies appeared to influence the development of neuropathy. One of the important manifestations of diabetic neuropathy, the reduction in maximum conduction velocity of peripheral nerve fibers, was demonstrated in this study. A significant correlation was found between the reduction in maximum conduction velocity of peripheral motor nerve fibers and the presence of diabetic microangiopathies. Although treatment of diabetic neuropathy with large doses of several vitamins was attempted, improvement was noted in only a small percent of cases, and the effectiveness of such therapy is doubtful.
While the frequency of diabetic neuropathy was about the same in Japan as in westenrn countries, it occurred in a milder form, as did the biochemical and angiopathic manifestations of diabetes.
