抄録
Variations in the electrophoretic pattern of plasma protein were studied with patients showing lingual signs or angular stomatitis related to riboflavin-deficiency, and following results were obtained. 1) Low albumin, high γ-globulin and low albumin-globulin ratio were found to be closely correlated with the above mentioned signs, both developing with increase in riboflavin-deficiency. These variation were more marked in the patients showing furring on their tongues (group A) than in those without it (group B). 2) Low albumin and albumin-globulin ratio and high γ-globulin were more marked in the patients showing atrophy of papillae, edema, violet-red coloring, fissure formation on the tongue and angular stomatitis and less marked among those showing red-coloring or proliferation of papillae. These variation were more eminent in group B than in group A. 3) In group B, the ester ratio of riboflavin or riboflavin-ester concentration of blood was found to correlate with albumin concentration and reversely with γ-globulin. In group A the correlation between the ester ratio and albumin concentration only was found. 4) Riboflavin deficiency was evidenced to be related closely with liver damages and hypoproteinemia. So it should be kept in mind that a vicious circle will be effected between the riboflavin deficiency and the liver damage or hypoproteinemia.
