抄録
In order to clarify whether the γ-ray irradiation caused directly the fluctuation of riboflavin distribution in the rat body, or some secondary changes brought about by the irradiation exerted any influence, the following experiments were made. Effects of the decrease of diet uptake caused by the irradiation were examined by feeding on a group of normal rats with the same amount of diet taken by the animals which had been subjected to the irradiation of 2000 r of γ-ray all over the body. The results showed that the irradiation caused a characteristic fluctuation of riboflavin distribution in the body, although an increase of the urinary excretion of the vitamin was observed even in the non-irradiated group. Furthermore, changes in visceral weight occurred in the irradiated animals. The most striking effect was observed in the spleen. The weight of the organ was reduced to 1/3 of the original 72 hours after the γ-ray irradiation of 2000 r. Water content of various viscera was almost constant. Decomposition of free riboflavin in a solution under an intensive γ-ray irradiation was in a slight degree.
