抄録
S-Benzoylthiamine monophosphate (BTMP) has a higher affinity to animal tissues than thiamine hydrochloride. To clarify the chronic toxicity in large doses of BTMP when for a long period, the rats were fed on a diet containing 1000 ppm of BTMP and sacrificed after one year. With this dose applied, no remarkable histological change was observed, suggesting that the chronic toxicity of BTMP is as low as that of thiamine hydrochloride.