抄録
The young albino rats of the Wistar strain were fed on the pantothenic acid deficient diet and the states of deficiency and of recovery after the administration of calcium D-panto-thenate or DL-pantothenol were observed by their body weights. The levels of the vitamin in chief organs of the animals were measured by microbioassay using Lactobacillus arabinosus for free pantothenic acid and by enzymatic sorbyl-CoA formation for CoA. Both free pantothenic acid and CoA were reduced in a deficient state of 3 week's duration, especially the decease of free pantothenic acid was pronounced. In the recovery states after loading both pantothenic acid derivatives, the levels of free pantothenic acid of the both test groups were a little higher than that of the control group, while those of CoA were almost same as that of the control. No difference between two groups of loading Ca-pantothenate and pantothenol was found.
