The effect of vitamin A on the urinary excretion of 17-KS in rat was studied. The determination of the urinary excretion of 17-KS was carried out by the modified method of Drekter, twice a week. No significant change in the excretion of 17-KS was found in the groups which were injected intramuscularly with 100,500 and 1,000 I.U. of vitamin A daily. These findings suggest that vitamin A have no significant effect on the function of adrenal cortex and ovaries.
