ビタミンB_1のミクロオートラジオグラム : (III)経口投与時のマウス眼球のThiamine-^3HおよびO-Benzoylthiamine disulfide-^3Hのとりこみ

抄録

Uptake of thiamine-^3H(B_1-^3H) and O-benzoylthiamine disulfide-^3H(BTDS-^3H) in eyes of mice with an oral administration has been studied by microautoradiography. The most marked uptake of B_1-^3H and BTDS-^3H was demonstrated in the retina and optic nerve. In the iris and ciliary body a moderate uptake was seen, while the cornea showed slight uptake of B_1-^3H and BTDS-^3H. In the retina a large amount of grains was observed in the layer of rods and cones, and then in ganglionic layer and layer of nerve fibers. In the iris and ciliary body distribution of the grains was most markedly observed in muscle fibers and then in the lining epithelium. Grains in the cornea was found in the basal layer. Uptake of BTDS-^3H was more marked than B_1-^3H in each portion of the eyes.