抄録
Vitamin B12 compounds are synthesized by only certain bacteria, thaumarchaeota, and cyanobacteria in marine system. Cyanobacteria do not synthesize vitamin B12 but rather produce pseudovitamin B12 , which is inactive in some microalgae as well as humans. Thus, vitamin B12 and pseudovitamin B12 co-exist in the surface ocean (photic zone, depth 0–200 m). Thaumarchaeota is the major producer of vitamin B12 in the deeper ocean (mesopelagic zone, depth 200–300 m). Pseudovitamin B12 formed by cyanobacteria can be remodeled to vitamin B12 by some microalgae. As almost half of the species of algae require vitamin B12 , such biological interactions over vitamin B12 play pivotal roles in algal growth. Vitamin B12 synthesized by certain bacteria and thaumarchaeota is transferred via algae and then concentrated into fish and shellfish bodies in the marine food chain.