YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
一般論文
薬物とアルミニウム(III)との錯生成判定のための簡易スクリーニング法
宮地 加奈子中尾 昌弘黒川 央富田 真由神野 伸一郎森山 健三山口 敬子藤田 芳一
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2009 年 129 巻 12 号 p. 1551-1558

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  We examined a simple screening method for judging the complex formation between a drug and aluminum(III) on a spot plate. As few drug had color reaction by basing on the binary complex formation of drug-aluminum(III), the ternary complex formation of drug-aluminum(III)-dye was studied this time using 50 kinds of drugs. The dyes used were Chromazurol S and Erythrosin. As a result, in the drug that the complex formation with aluminum(III) was assumed, a remarkable coloration difference was recognized in comparison with the blank prepared under the same conditions. The proposed simple screening method should be very useful for judging instantly the complex formation between a drug and aluminum(III).

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© 2009 by the PHARMACEUTICAL SOCIETY OF JAPAN
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