YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
酸素存在下におけるアミノフィリン水溶液の光安定性
石黒 義信沢田 勝田中 安子河部 靖
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1980 年 100 巻 10 号 p. 1048-1053

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The photo-stability and the structures of photo-oxidation products of aminophylline in aqueous solutions were investigated. When an aqueous solution of aminophylline was submitted to photo-oxidation in the presence of oxygen under daylight, aminophylline was decomposed to yield 1, 3-dimethylallantoin, N, N'-dimethyloxamide and ammonia as main products. It was found that photodegradation of theophylline in an aqueous aminophylline solution was closely related to that of ethylenediamine in the same solution.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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