抄録
Artemisiae capillaris FLOS is one of the oldest Chinese medical plants as antiinflammatory, antipyretic, choleretic and diuretic agants in the case of liver disorder and yellow disease. In order to clarify the pharmacological significant substances in this plant, some pharmacological activities, especially antiinflammatory (Whittle's method, carrageenin edema, thermal edema) and analgesic (Whittle's method, hot-plate method, Haffner's method) effects were examined in mice and rats. A main coumarin derivative in A. capillaris, 6, 7-dimethylesculetin, showed antiinflammatory, analgesic and choleretic properties. It can be assumed that the measurement of 6, 7-dimethylesculetin content is one of the parameter for the evaluation of this crude drug.