YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
生薬の生物活性成分に関する研究 インチンコウの薬理学的品質評価その1
山原 條二松田 久司沢田 徳之助壬生 寛之藤村 一
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1982 年 102 巻 3 号 p. 285-291

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Artemisiae capillaris FLOS is one of the oldest Chinese medical plants as antiinflammatory, antipyretic, choleretic and diuretic agants in the case of liver disorder and yellow disease. In order to clarify the pharmacological significant substances in this plant, some pharmacological activities, especially antiinflammatory (Whittle's method, carrageenin edema, thermal edema) and analgesic (Whittle's method, hot-plate method, Haffner's method) effects were examined in mice and rats. A main coumarin derivative in A. capillaris, 6, 7-dimethylesculetin, showed antiinflammatory, analgesic and choleretic properties. It can be assumed that the measurement of 6, 7-dimethylesculetin content is one of the parameter for the evaluation of this crude drug.
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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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