YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Effects of Amount of Bridging Liquid on the Growth Process and the Compaction Process of Agglomerate in Wet Spherical Agglomeration
Yoshiaki KAWASHIMAKoji NIWAHirofumi TAKEUCHITomoaki HINOToshiyuki NIWA
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1990 Volume 110 Issue 8 Pages 591-597

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Abstract
Effects of the amount of bridging liquid on the growth and compaction processes of wet spherical agglomeration were studied by using glass beads as model powder. Compaction of agglomerate was enhanced by increasing the amount of bridging liquid used, producing the mechanically strong agglomerate with low porosity, i. e. large coordination number. Compaction process of agglomerate was represented by the modified Kawakita's equation. When the degree of saturation of voids in agglomerate with bridging liquid (Rf)<0.6, the growth process of agglomerate was described by use of a non-random coalescence mechanism and a coalescence mechanism at the later stage with Rf≒1.0.
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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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