YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
尿素配合クリーム中の尿素の液体クロマトグラフ法による定量と安定性評価
安田 勉赤間 敏寛井川 宏司
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ジャーナル フリー

1992 年 112 巻 2 号 p. 141-145

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A method was developed for determining urea in urea creams by high-performance liquid chromatography using strong acidic cation exchange gel. Elution was carried out with 0.05 M phosphate buffer (pH 3.4) at 40°C, and detection was made with a UV-spectrometer at 200 nm. This method was used for studying and comparing the stability of urea creams produced by ourselves and by other manufactures. The assay showed that there were differences in the stability of the tested creams.
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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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