Abstract
The present experiments were undertaken in order to obtain 2-amino-4-methylpyrimidine from 2-amino-4-methyl-6-chloropyrimidine. Use of Zn for the dehalogenation of this reaction gives a very poor yield but addition of NaOH to Zn powder increases the yield to 75%. Use of methanol or 60% methanol as soevent in this reaction gives 2-amino-4-methyl-6-methoxypyrimidine, m.p. 158°, with a good yield, and the objective compound cannot beobtained.
