Abstract
Condensation of the Na-salt of p-thiocresol and 2-phenylamino-4-chloromethylthiazole, obtained from phenylthiourea and dichloro-acetone, results in 2-phenylamino-4-p-toylmercaptomethylthiazole. Oxidation of the latter gives 2-phenylamino-4-p-tolylsulfonemethyl-thiazole, m.p. 158-9°, which coincides with a compound obtained by the condensation of phenylthiourea and α-bromo-α′-p-tolyl-sulfone-acetone. From these facts, it is clear that the substance obtained generally by the condensation of α-bromo-α′-arylsulfone-acetone and thiourea is a compound of 4-arylsulfonemethylthiazole.
