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Predecessor
Volume 69, Issue 1
Displaying 1-14 of 14 articles from this issue
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Eiji Ochiai1949Volume 69Issue 1 Pages 1-8
Published: January 15, 1949
Released on J-STAGE: February 19, 2010
JOURNAL FREE ACCESSDownload PDF (1927K) -
Shigehiko Sugasawa1949Volume 69Issue 1 Pages 8-14
Published: January 15, 1949
Released on J-STAGE: February 19, 2010
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[in Japanese], [in Japanese]1949Volume 69Issue 1 Pages 15-21
Published: January 15, 1949
Released on J-STAGE: February 19, 2010
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Structure of Epistephanine from its Absorption SpectrumMasao Tomita, Shojiro Uyeo, Sadaki Sawa, Kazuo Doi, Toshiko Miwa1949Volume 69Issue 1 Pages 22-25
Published: January 15, 1949
Released on J-STAGE: February 19, 2010
JOURNAL FREE ACCESSAbsorption spectrum of epi-stephanine was compared with those of a large number. of compounds of dihydro isoquinoline series in order to discuss the structure of epi-stephanine.View full abstractDownload PDF (674K) -
Nitration of Di- and Tri-ethyleneglycolTakeo Ishiguro, Sadatake Katoo, Seiken Yagyu1949Volume 69Issue 1 Pages 25-27
Published: January 15, 1949
Released on J-STAGE: February 19, 2010
JOURNAL FREE ACCESSExaminations were made of the nitration of diethlene- and triethylene-glycol by the use of acid mixtures of various conditions in the ranges of dehydration values of 1.61 to 5.00. The melting and boiling points, and specific gravity of diethylene-glycol dinitrate were determined. At a low pressure following equation can be given: logt=0.096logp+2.0534 where t is the boiling point in °C and p, vapor pressure in mm. Properties, specific gravity and boiling point of triethylene-glycol dinitrate were determined.View full abstractDownload PDF (601K) -
Syntheses of Sulfaminopyrimidines. (2)Taizo Matsukawa, Makoto Yoshida1949Volume 69Issue 1 Pages 27-33
Published: January 15, 1949
Released on J-STAGE: February 19, 2010
JOURNAL FREE ACCESSTwelve kinds of 2-p-aminobenzene-sulfaminopyrimidine compounds were synthesized by the reaction of p-acetaminobenzene-sulfonamide and various compounds of 2-methyl (or ethyl)-mercaptopyrimidine.View full abstractDownload PDF (1172K) -
Synthesis of 5, 6-Dimethoxy-8 (δ-diethyl-amino-α-methyl-n-butyl)-aminoquinolineSuyeo Tatsuoka, Jisaburo Ueyanagi, Tomoji Kinoshita1949Volume 69Issue 1 Pages 33-36
Published: January 15, 1949
Released on J-STAGE: February 19, 2010
JOURNAL FREE ACCESS5-Halogen compounds of 6-methoxy-8-nitroquinoline obtained by the direct chlorination or bromination of the latter were methoxylated and reduced, by which 5, 6-dimethoxy-8-aminoquinoline was obtained. Condensation of this with α-diethylamino-δ-pentanone-diethylacetal to Schiff's base and subsequent reduction gave the objected compound listed in the subtitle. This gives crystalline salt by condensation with 2-hydroxycinchonic acid.View full abstractDownload PDF (899K) -
4-Diethylaminobenzyl-phenylalkyl-aminesShinkichi Niinobe1949Volume 69Issue 1 Pages 37-39
Published: January 15, 1949
Released on J-STAGE: February 19, 2010
JOURNAL FREE ACCESSFive kinds of 4-diethylamihobenzyl-phenylalkyl-amine were newly synthesized and their local anaesthetic actions were tested by rabbits' cornea test and their toxicity (LD 50) with guinea pigs.View full abstractDownload PDF (708K) -
Takeo Tsukamoto, Toshio Tominaga, Junji Takahashi1949Volume 69Issue 1 Pages 40-41
Published: January 15, 1949
Released on J-STAGE: February 19, 2010
JOURNAL FREE ACCESSQuercetin was isolated from the alcohlic extract of the leaves of Euphoria Longana Lam., and was proved by mixed fusion as pentacetyl-quercetin. A glucoside assumed to be quercitrin was isolated from crude tannin but values did not coincide with the published facts. This was thoroughly methylated by diazomethane, decomposed by dil. H2SO4, and pale-yellow, methylated aglycone, m.p. 191-2°, was obtained. This was proved by mixed fusion to be 3-hydroxy-5, 7, 3′, 4′-tetramethoxyflavone, m.p. 192°, which was prepared from rutin obtained from the flowers of Sophora japonica L. This proved that the bonding of sugar was at 3-position so that the glucoside must inevitably be quercetin-3-rhamnoside, i.e. quercitrin. Although there is a slight differences in the melting point from that found in literature it must be quercitrin as was earlier found by Mr Ohta (J. Pharm. Soc., Formosa. 53 (1942)).View full abstractDownload PDF (560K) -
Toshio Tominaga1949Volume 69Issue 1 Pages 41-43
Published: January 15, 1949
Released on J-STAGE: February 19, 2010
JOURNAL FREE ACCESSA glucoside was isolated from the alcoholic extract of the leaves of Leucaena glauca Benth. The yield, about 0.0% of the leaves. The aglycone of this glucoside is quercetin and the sugar, rhamnose, and quantitative determination proved this to be quercetin-monorhamnoside. Thorough methylation of this glucoside with an excess of diazomethane and subsequent hydrolysis gave 3-hydroxy-5, 7, 3′, 4′-tetramethoxy-flavone Which proves that the original glucoside was quercetin-3-rhamnoside, i.e. quercitrin.View full abstractDownload PDF (695K) -
Syntheses of 2 amino-5-p-chloro-benzenesulfone-thiazole DerivativesMasaki Ohta, Rokuro Sudoh1949Volume 69Issue 1 Pages 43-47
Published: January 15, 1949
Released on J-STAGE: February 19, 2010
JOURNAL FREE ACCESSSyntheses of the derivatives of 2-amino-5-p-chlorobenzene-mercapto- or -sulfone-thiazole from p-chloropheny-mercapto-ketone, -sulfone-ketone or -mercapto-acetal are explained. The latter 3 compounds are obtained by the condensation of p-chlorothiophenol or p-chlorobenzenesulfinic acid and chloro-acetone, chloro-acetophenone or bromacetal, respectively.View full abstractDownload PDF (875K) -
Arylmercapto- and Arylsulfone-ketonesMasaki Ohta, Rokuroh Sudoh, Kikumasa Satoh1949Volume 69Issue 1 Pages 47-50
Published: January 15, 1949
Released on J-STAGE: February 19, 2010
JOURNAL FREE ACCESS1) Mechanisms of alkaline decomposition were observed of arylmercapto- and arylsulfone-ketones.
2) Halogenation of arylmercapto-acetone results in the substitution of halogen atom in the methylene radical situated next to S-atom. In the case of arylsulfone-acetone, however, halogen goes in the methylene radical next to -SO2- group which, under the presence of hydrogen halides, transits in majority of cases to the methyl radical at the end.
3) Halogen compounds of arylmercapto-ketone are generally unstable and decomposes upon heating with alcohol.View full abstractDownload PDF (817K) -
2-Phenylamino-4-p-tolylsulfone-methylthiazoleMasaki Ohta, Takeaki Katoh1949Volume 69Issue 1 Pages 50-51
Published: January 15, 1949
Released on J-STAGE: February 19, 2010
JOURNAL FREE ACCESSCondensation of the Na-salt of p-thiocresol and 2-phenylamino-4-chloromethylthiazole, obtained from phenylthiourea and dichloro-acetone, results in 2-phenylamino-4-p-toylmercaptomethylthiazole. Oxidation of the latter gives 2-phenylamino-4-p-tolylsulfonemethyl-thiazole, m.p. 158-9°, which coincides with a compound obtained by the condensation of phenylthiourea and α-bromo-α′-p-tolyl-sulfone-acetone. From these facts, it is clear that the substance obtained generally by the condensation of α-bromo-α′-arylsulfone-acetone and thiourea is a compound of 4-arylsulfonemethylthiazole.View full abstractDownload PDF (364K) -
Reaction of Grignard Reagent on Pyridine-N-oxideEiji Ochiai, Koh Arima1949Volume 69Issue 1 Pages 51-54
Published: January 15, 1949
Released on J-STAGE: February 19, 2010
JOURNAL FREE ACCESSIn order to observe the reaction of Grignard reagents on pyridine-N-oxide and its derivatives, the author re-examined the studies made by Colonna (C. A. 30, 3420) on pyridine-N-oxide. Ethereal solution of phenyl-MgBr was added to the anhydrous benzene solution of pyridine-N-oxide. Treatment of reaction products revealed formations of α-phenylpyridine and diphenyl-dipyridyl, the latter being assumed as γ, γ′-dipyridyl. These results show that the reaction of pyridine-N-oxide and phenyl-MgBr proceeds as in (A) (Cf. Figure in the original text) forming α-phenylpyridine. Polymerization from (II) is difficult to realize, for the formation of diphenyldipyridyl and it is assumed that the reaction proceeds as in (B) through (III). Yields of α-phenylpyridine and diphenyldipyridyl are comparatively low and the ratio of their formation is about 8:5.View full abstractDownload PDF (836K)
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