チフス菌の発育素に関する研究 (第1報)
ペプトン中のチフス菌発育素に就いて
1950 年 70 巻 6 号 p. 311-319
詳細
1950 年 70 巻 6 号 p. 311-319
The conclusion was drawn that the chief growth factor in peptone against Shikata strain of typhoid bacillus was tryptophane, from following reason:
1) The fraction obtained by the solvent extraction of peptone and its treatment by esterification, etc., possessed the most growth promoting effect in the one giving positive reaction to tryptophane coloration.
2) The fractionation of peptone by the adsorptive affinity to active charcoal showed that those having adsorptive affinity possessed growth promoting effect, the affinity being in direct proportion to the content of tryptophane.
3) The rise and fall of tryptophane in the pancreatin digested product of casein is approximately in direct proportion to the growth promoting effect and the rise and fall of amino form nitrogen has little, if any, effect.
4) Pancreatin digest product of gelatine, a protein not containing any tryptophane, does not have any effect of growth promotion.
5) The growth promoting effect of the pepsin digested product of casein is also in approximate proportion to the tryptophane content. Moreover, strepogenin has no relationn to the growth of typhoid bacillus.
