抄録
1) As a new method of preparing chemically pure isovaleric acid, the following process was worked ont: acetone→diacetone alcohol→mesityl oxide→β, β-dimethylacrylic acid→isovaleric acid.
2) dl-α-bromoisovaleric acid, prepared from such isovaleric acid, was resolved into optical isomers by the use of optically active 1-phenyl-2-methylaminopropane, and D(-)- and L(+)-α-bromoisovaleric acids were obtained.
3) From these optical isomers the two isomeric bromovalerylurea were prepared by the oridinary method as D(-)- bromovalerylurea, m.p. 158.5-159.5°, [α]D10-26.0 (c=3, EtOH), and L(+)-bromovalerylurea, m.p. 158.5-159.5°, [α]D10+26.0° (c=3, EtOH).
