抄録
The total alkaloid of the Scopolia root was precipitated from its cold extract of 0.5% H2SO4 by the Dragendorf reagent and the bismuth compound of the alkaloid obtained by its filtration was decomposed by calcium hydroxide. The free alkaloid thus obtained was extracted with amyl acetate, shaken with diluted sulfuric acid and again precipitated by potassium carbonate. The precipitate was recrystallized from carbon tetrachloride and l-hyoscyamine, m.p. 102°, was obtained in an yield of 83% of the total alkaloid. l-Hyoscyamine easily underwent racemization by cold 0.2% sodium hydroxide solution to atropine.
