抄録
Action of 2-thiocoumarin against ascaris was examined with nerve muscle and muscle preparation of ascaris, and by the forward movement of ascaris, and following results were obtained:
1) After application of the compound to nerve muscle preparation of ascaris, increase in bending motion and tonus was observed (samples I and V), or the appearance of bending or curling motion (samples II and IIIA).
2) In muscle preparation (samples IIIB and IV), no change was observed after application of the chemical.
3) The forward motion of ascaris being observed in U-shaped glass tube disappeared shortly after application of the chemical, and the ascaris simply moved its fore portion, or curled itself. The curling motion was most prominent in 1, 000 dilution of the chemical.
From the foregoing results, 2-thiocoumarin was assumed to stimulate the nerve system (including the nerve centers in the head region) of ascaris.
