YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
非水溶液滴定による医薬品の定量 (第10報)
氷酢酸を溶媒とする有機塩基と無機及び有機酸との塩の滴定に及ぼす酸の影響について
鹿島 哲加納 宏一郎
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ジャーナル フリー

1956 年 76 巻 1 号 p. 50-53

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The effect of the combined acid on the direct titration of the salts of organic bases and inorganic or organic acids with perchioric acid in glacial acetic acid was comparatively examined by the titration curves obtained by the potentiometric titration of the salt of diphenhydramine and various acids with glass-calomel electrode. It was thereby found that the order of the strength of the acids in glacial acetic acid was almost equal to their strength in aqueous solution. It may be concluded that weak acids with dissociation constants below 10-3 would be almost without effect on the titration but stronger acids would lower the measurement accuracy.
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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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