芳香族硫シアン及び関連化合物の合成並びに生物学的試験 (第4報)

芳香族硫シアンニトロ化合物の合成

抄録

Since there are many antibacterial substances such as chloramphenicol and Furacin which contain a nitro group, the effect of the nitro group to animals seemed of interest. In order to test the change, if any, of physiological action by the introduction of a nitro group in aromatic thiocyano compounds, a series of aromatic thiocyanonitro compounds were prepared. Of such compounds synthesized, the present paper describes 19 new compounds besides 2-ethoxycarbonyl-4-thiocyano-3′-nitrobenzanilide, 2-carboxy-4-thiocyano-4′-nitrodiphenylurea, and 2, 3′-dinitro-4-thiocyanobenzanilide.