芳香族硫シアン及び関連化合物の合成並びに生物学的試験 (第5報)
芳香族硫シアンニトロ化合物の対生物作用について
1956 年 76 巻 3 号 p. 316-319
詳細
1956 年 76 巻 3 号 p. 316-319
Biological activities of aromatic thiocyano compounds, substituted with nitro group in the ring or in the side chain, were tested against Staphylococcus aureus, Escherichia coli, and Rabdias bufonis. It was thereby found that antibacterial and rabdiacidal activities were present in compounds of the general formula, R1 -SCN, in which R1 is substituted with a fat-soluble group, such as -NHCONHC6H4NO2 (p), and R2 is substituted with an electrophilic and non-dissociating group, such as -NO2 and -COOC2H5.
