ゼラチン, コンドロイチン硫酸混合膜の物理化学的研究(第3報)電解質透過性およびそのpH変化

抄録

The mixed membranes were prepared from gelatin and chondroitinsulfate (chs), whose fractions (X_chs) were 0.0, 0.108, 0.226, and 0.317. They were cross-linked by formaldehyde. The permeability of electrolytes (KCI and CaCl₂) through the membranes and their pH dependence were investigated in order to elucidate the effects of X_chs and the formation of complex between gelatin and chs on the permeability. The permeability (P^*) of KCl and CaCl₂ decreased with the content of the membrane constituent (W_M). The effect of X_chs on P^* depended on the kind of electrolytes ; permeability of KCl decreasded with increasing, X_chs but that of CaCl₂ was independent of it. In a strongly acidic region, effect of the concentration of hydrogen ion on P^* (KCl as solute) varied with the fraction of chs (X_chs) ; permeability through the membranes with X_chs=0.0 and 0.108 increased as pH of the bulk solution departed from the isoionic point of gelatin (pH 4.9), but that through the membrane of X_chs=0.226 decreased apparently at pH 2.2. For these systems, the relations between W_M and pH, and between P^* and W_M were investigated at various pH. From these results, it was found that the formation of the insoluble complex repressed the swelling of the membrane and decreased P^*.