拡散理論の"帯培養法"への応用(第2報)実験による理論の確認

抄録

Experimental verification of the theory in the"band culture method"was carried out by using various drugs and various bacteria, and it was clarified that the method is more sensitive than the two-dimensional diffusion system (cup method). The relation between the length of clear zone and the drug concentration, and the relation between the minimum growth inhibitory concentration (MIC) and the initial bacteria concentration closely resemble the simulation results presented in a preceding report. The drug release from the gelatinous (gel-type) ointment base is faster than that from petrolatum. This result can be applied to the assessment of an ointment base.