複素環式化合物の合成研究(第717報) : Methylenomycin A メチルエステルと求核試薬としての数種のアミンとの反応について
1977 年 97 巻 8 号 p. 944-947
詳細
1977 年 97 巻 8 号 p. 944-947
Methylenomycin A methyl ester (II) was synthesized from methylenomycin (I) in a high yield, and reaction of the resulting ester with several amines as a nucleophile afforded the adducts of 2-substituted 5, 6-epoxy-5, 6-dimethylperhydrocyclopenta [c] pyrrole-1, 4-diones (IIIa-VIIa) or s-substituted 2, 3-epoxy-2, 3-dimethyl-4-oxocyclopentane-1-carboxylates (VIIIa, IXa).
