The aim of our study was to ascertain whether the specific Bifidobacterium animalis DN-173 010 fermented milk could modulate colonic transit time in humans. Bifidobacteria are a major component of the gut microflora and may interact with gut transit. Methods: The trial compared in a parallel double blind study in seventy two healthy volunteers the effect of a Bifidobacterium animalis fermented milk containing 2.6×108 CFU/g living bifidobacteria versus heat-treated Bifidobacterium fermented milk on colonic transit times. The main marker was the total colonic transit time (CTT) measured with radio-opaque pellets. Segmental colonic transit times were also calculated. Results: A 11-day-consumption of this Bifidobacterium animalis DN-173 010 fermented milk significantly reduced the total CTT (-20.6%) comparatively to the initial CTT and to the control group where no significant change were recorded. The effect was more pronounced in women than in men. Conclusion: Our study demonstrated that the consumption of the fermented milk containing living Bifidobacterium animalis DN-173 010 was able to improve CTT in humans.
Extracts of several Oriental and European herbs were tested for their inhibitory effects on volatile sulfur production in pig in vitro cecal fermentation. Some of the extracts, namely, Marrubium vulgare and Perilla frutescens, significantly decreased volatile sulfur and ammonia production. The present results indicate that some herb extracts might improve fecal malodor and possibly host health.
Methanethiol and hydrogen sulfide generated from feces present an environmental issue in the intensive field of animal agriculture. We have identified four strains of clostridia and five others as methanethiol producers from a range of laboratory strains, which may be present in the large intestines of livestock. We have also isolated one Clostridium perfringens from pig feces as a potent producer of methanethiol. Unlike methanethiol from L-methionine, manylaboratory strains produced hydrogen sulfide from L-cystine.