Cephalometric radiographs of cleft lip and/or cleft palate patients taken at the time of either cheiloplasty or palatoplasty were analyzed in order to see the variations in craniofacial morphology with in the same cleft type.
The samples studied were 392 lateral head films consisting of 48 of unilateral cleft lip (UCL),110 of unilateral cleft lip and alveolus (UCLA),129 unilateral cleft lip and palate (UCLP), and 105 of isolated cleft palte (CP). Samples of any patients with associated syndrome were excluded. Bilateral cleft lip and/or palate were too few to analyze statistically, so this cleft type was not studied.
The measurement of ten dimensions and seven angles were use d for the analysis of craniofacial morphology and body weight and height were used to evaluate the patient's body structure.
1. The samples of each cleft type were first divided into male- and female-group, and the sex differences in body structure as well as craniofacial morphology were studied.
No sex differences were observed in UCL. Body structure was larger in the male group in UCLP and CP. The size of cranium (Ba-V, G-Op), the cranial base length (S-N, N-Ba), and the upper facial heig ht (N-Ans) were found to be significantly larger in the male group in UCLA, UCLP, and CP. In U CLP, mandibular length was shorter in the female-group.
2. Cluster analysis was next made to see whether each cleft type could be further classified into subtypes.
The female-group of UCL, UCLA, UCLP and CP were significantly grouped into three subtype s (good, moderate, and poor facial growth). On the other hand, the male group of UCLP and CP was divided into two subtypes (good, poor facial growth).
The size of cranium, cranial base length and upper facial height were selected as the best discriminators in the cluster analysis of the types of cleft lip with or without cleft palate.
In CP, the mandibular length (Go-Me) was selected, in addition to the above five items. In the case of CP, significant differences were observed in the occurrence rate of associated anomalies among the three subtypes thus classified.
View full abstract