Eye tracking while driving a car in a straight, no-oncoming car and paved road of driving simulator was analyzed. Subjects were diagnosed as normal by ophthalmologic examination and they had normal visual field. Three of seven subjects were female and others were male and the median of the age of subjects was 47. (range: 25 – 67years old). Eye tracing data during driving a car in 3 seconds for 3 different scenes was observed for each subject. There found no significant difference between male and female or young and old. The subjects whose proportion of the points of regard concentrated in the area less than 3 degrees from the center of the eye movements were 10 cases of total 21 case (47.6%). Intra individual difference among scenes seemed also non-negligible. The results suggested the inter- and intra- individual difference in eye tracking while driving a car.

Medication adherence is a significant foundation of medical therapy. However, some research have shown that almost half of patients do not completely take the prescribed medication. The aim of this study was to assess the effect of the “medication reminder alarm” as our smartphone application for medication adherence.

A total of 201 monitors were assigned to four groups, and each group used the “medication reminder alarm” for dif-ferent time period. In these experiments, monitors opened a package in imitation of dosing three times a day for 4 weeks, and we compared the adherence rates between each of the different groups.

In the same group, the adherence rates in the period in which the monitors used the “medication reminder alarm” were significantly higher than those in the period in which they did not use the alarm. In addition, the group that used the “medication reminder alarm” for 4 weeks kept high adherence rates throughout all the experiments. In contrast, the group that used the “medication reminder alarm” for the first 2 weeks exhibited significantly lower the adherence rates than those of the last 2 weeks.

These results indicate that our “medication reminder alarm” effectively increased the adherence rates, indicating that this application could be a useful tool to increase medication adherence in patients in routine clinical practice.