[in Japanese]

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Reconstruction of the right ventriclar outflow tract (RVOT) in congenital heart disease often requires implantation of a valved conduit. A hand-made expanded polytetrafluoroethylene (ePTFE) trileaflet Dacron graft conduit has been used at our center since 1997, and has been implanted in 31 patients. Midterm results of this conduit were investigated in 30 of the patients who have been followed at our outpatient clinic. There were 16 males and 14 females. The mean age and body weight were 16.4±7.2 (range, 3.4-33.4) years and 41.7±13.3 (range, 13.0-64.0)kg, respectively. Diagnoses were tetralogy of Fallot with pulmonary atresia in 14 patients, RVOT reconstruction associated with Ross procedure in 8, transposition with pulmonary stenosis in 3, pulmonary atresia with intact ventricular septum in 2, tetralogy with absent pulmonary valve syndrome in 1, pulmonary regurgitation developed after tetralogy repair in 1, and hemitruncus in 1. The median size of the graft was 22 (range, 20-26)mm. All patients were in NYHA functional class I at the time of the latest follow-up. The pressure gradient across the conduit was 11.0±5.8mmHg during the same hospitalization and 13.8±6.5mmHg on the latest echocardiogram (Interval, 2.4±1.5 years, p=0.85). The valve function was well maintained in all patients, with the regurgitation graded as non-trivial in 22 patients, mild in 7, and moderate in only 1. Midterm results of hand-made ePTFE trileaflet valved cunduit was satisfactory. A longer follow-up is mandatory to assess its actual durability.

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This study evaluated factors influencing residual aortic regurgitation (AR) after valve re-suspension surgery for acute type A aortic dissection. From January 1996 through December 2002, 63 patients were treated for acute type A dissection at our institution. Among these 63 patients, pre-and postoperative echocardiograms were available in 38 patients who underwent surgery combined with native aortic valve re-suspension. These 38 patients were divided into 2 groups according to the postoperative AR grade, i. e.: AR group: AR grade≥II (n=6), no-AR group: AR grade≤I (n=32). The severity of pre and postoperative AR was assessed by transthoracic or transesophageal echocardiography. The preoperative diameters of mid ascending aorta and sinotubular junction, and the percentage of the circumference of the dissection at the sinotubular junction level was measured by enhanced CT scan. Preoperative patient backgrounds were similar in both groups. The preoperative AR grade in the AR group was significantly greater than that of the no-AR group (2.25±1.17: 0.69±0.91, p<0.001). The tear was more frequently located in the ascending aorta in the AR group than in the no-AR group (66.7%: 37.5%, p<0.05). The percentage of circumference of the dissection at the sinotubular junction level did not affect the preoperative AR grade, but it did show a tendency to influence the severity of postoperative AR, though the difference was not significant. Three patients (7.9%) had AR grade III at the time of discharge, but did not clinically require further surgical intervention. Preoperative significant AR and the location of the tear in the ascending aorta are associated with postoperative residual AR after aortic valve re-suspension. The percentage of circumference of the dissection at the sinotubular junction level might influence the severity of postoperative AR.

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We treated 162 patients by isolated CABG with a left internal thoracic artery (LITA) anastomosed to the left anterior descending artery and a radial artery anastomosed to the circumflex artery between August 1996 and December 2002. Late angiograms were performed 6 to 65 months (21.7±15.8) after the operation. The purpose of this study was to compare midterm results of radial arteries anastomosed to the side wall of LITA (group Y) with those anastomosed to the aorta (group AC). There were no operative deaths in either group and no difference in the postoperative complication rate including cerebral infarction. The early patency of group Y was lower than that of group AC (group AC: 97.8%, group Y: 87.1%, p=0.017), and also the late patency of group Y was significantly lower than that of group AC (group AC: 90.9%, group Y: 36.4%, p=0.0008). All of the early patent radial artery grafts in group AC were patent on late angiograms, but 3 of the 25 anastomoses in group Y which were clearly patent on early angiograms later showed a string sign later. When using a radial artery graft in circumflex artery territory, we recommend an aorto-coronary bypass graft rather than Y-graft.

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The cause of atrial fibrillation (AF) after coronary artery bypass grafting (CABG) is not clear yet. Speculating that the extension of pulmonary vein (PV) would induce AF after CABG, we analyzed 39 cases in which a Swan-Ganz catheter was inserted at the onset of AF. The cardiac index (CI), systolic pulmonary artery pressure (sPA), diastolic pulmonary artery pressure (dPA) were measured continuously after operation. The “occupation index” was defined as “(value just before the AF onset-minimum value)/(maximum value-minimum value) × 100%.” The mean values of the occupation index for CI, sPA and dPA were 16±30%, 77±36%, 76±38% (mean±SD) respectively. Furthermore, cases in which CI just before the AF onset showed a minimum value in all the collected data consisted of 27 of the 39 cases (69%), and sPA/dPA just before the AF onset showed a maximum value in all the collected data in 26/25 of the 39 cases (67%, 64%). About two-thirds of AF cases occurred in the descending phase of CI, and in the ascending phase of sPA/dPA. We considered these conditions to be equivalent to the extension condition of PV and surmised that PV extension might be one of the causes of AF after CABG.

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We describe a case where a thrombus was effectively removed with a 20 Fr argyle^® thoracic catheter (Nippon Sherwood Medical Industries Ltd.) and the life of the patient was saved by thrombectory for an acute pulmonary thromboembolism. The patient was a 43-year-old woman. Emergency operation was indicated by a severe acute pulmonary thromboembolism and intracardiac floating thrombi afte an orthopedic surgery. A 20 Fr thoracic catheter connected to a cleaning type intraoperative blood salvage device was used to remove thrombi in a pulmonary artery and a good result was obtained. The advantages of this catheter include: 1) suitable hardness; 2) a protective round tip; 3) an aperture at the tip for the suction of small or crushabe thrombi and the removal of thrombi having a certain level of hardness with the shape intact; and 4) adjustable flexion of the catheter to easily detect a peripheral pulmonary artery. However, care should be taken when using the catheter to avoid damage to pulmonary artery walls.

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A 68-year-old woman received aortic valve replacement (AVR) with a Freestyle stentless valve using a subcoronary technique for aortic stenosis and regurgitation in September 2000. She complained of chest pain, had low grade fever and findings of inflammation and was admitted to our hospital with a diagnosis of acute myocardial infarction in December 2000. She suffered from repetitive or recurrent myocardial infarction. Transesophageal echocardiogram revealed no abnormal findings of the Freestyle stentless valve, but her blood culture was positive for methicillin-resistant coagulase negative Staphylococcus aureus (MRCNS) and she underwent an emergency operation. The Freestyle stentless valve was removed and replaced with a mechanical valve. The patient's intraoperative tissue grew MRCNS and parenteral antibiotics were administered for 8 weeks after surgery. Her condition was complicated with multiple cerebral infarction, however she was discharged on the 113th postoperative day and is doing well without recurrence of infection 12 months after the operation.

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We present a case of Marfan's syndrome with acute aortic dissection during the trimester of her pregnancy, who underwent a Bentall operation 2 days after emergency cesarean section. A 24-year-old woman during the 31st week of pregnancy visited our emergency room due to sudden onset of chest and back pain, though she had no abnormality until this event. Because of her tall height, spider fingers, positive wrist sign, visual disorder and scoliosis, she was given a diagnosis of Marfan's syndrome. Enhanced CT and cardiac ultrasonography revealed that she was suffering from acute aortic dissection with annulo-aortic ectasia. Since it was difficult for her to continue with her pregnancy, she underwent emergency cesarean section and gave birth to a male baby weighted 1, 706g. Although there was little likelifood of early thrombus formation in the false lumen or significant aortic regurgitation indicating an emergency operation, fear of massive bleeding from her uterus and the exfoliated surface of the placenta after cesarean section required an observation period of 2 days. We performed a Bentall operation successfully after careful sedation, ventilation and blood pressure control for 2 days.

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We report a case of arteriovenous fistula (AVF) secondary to spontaneous rupture of the right common iliac aneurysm into the right common iliac vein. In February 2003, an 81-year-old woman was admitted with dyspnea. Diuretics and digitalis were given under a provisional diagnosis of primary heart failure. Afterwards the heart failure turned out to be high output failure due to AVF. In June the patient complained of swelling of her right leg and was referred to our department. Ultrasonography to determine deep vein thrombosis of the right femoral vein revealed a dilatation of the left femoral vein, but there was no thrombosis. A pulse Doppler detected an arterial blood flow signal during early systolic pulse in the right femoral vein, confirming the suspicion of an AVF in abdominal cavity near this location. A pulsatile mass associated with bruit and thrill was palpable in the lower abdomen. Digital subtraction angiography showed a 50mm aneurysm of the right common iliac artery. Rapid visualization of the inferior vena cava and retrograde opacification of the right iliac vein indicated the presence of an AVF between the common iliac artery and vein. Operation was done by laparotomy on June 24, 2003. An occlusive balloon catheter was inserted from the right femoral vein and the balloon was dilated to patch the fistula before opening the aneurysm. After clamping the proximal and distal arteries the aneurysm was opened. By this maneuver there was no bleeding from the fistula. The AVF was closed from inside the aneurysm by 3 interrupted 4-0 monofilament sutures. The aneurysm was replaced with a prosthetic graft (Hemashield 8mm). The postoperative course was uneventful. The lower limb edema subsided and heart failure improved.

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A 44-year-old man underwent implantation of a DDD pacemaker for third degree heart block at age 20. The cutaneous pocket for the pulse generator was situated in the left pectoral region. He visited our hospital because of skin ulcer over the pacemaker without any other complaint such as fever or pain. The patient received a new DDD pacemaker system in the right pectoral region and old pacing leads were translocated under the pectoral muscle. However, right pectoral skin ulcer appeared 1 month later. Patch tests revealed a positive reaction to silicon. Wrapping of the pacemaker with a polytetrafluoroethylene (PTFE) sheet proved to be effective.

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A 24-year-old woman with an abdominal aortic aneurysm (AAA) caused by mucoid medial degeneration of the aortic wall in the absence of Marfan syndrome is reported. She required a Y-shaped graft replacement of the abdominal aorta through a minimal incision and recovered successfully.

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A 74-year-old man with renal failure had been treated with maintenance hemodialysis for 1.5 years at another hospital. The patient had an abdominal aortic aneurysm, bilateral iliac artery occlusion and coronary artery stenosis with a lesion in the left main trunk, but had been under observation because of the high risk of surgery. The patient elected to have surgery and was admitted to our hospital. We performed simultaneous surgery for severe coronary artery stenosis and abdominal aortic aneurysm with a maximum diameter of 85mm. The postoperative course was generally uneventful, but the patient required treatment of arrhythmia. We conclude that simultaneous surgery for angina pectoris and abdominal aortic aneurysm is feasible even in hemodialysis patients. It is important to pay attention to arrhythmia in the management of such patients, especially those with decreased cardiac function.

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We report a case of dysphagia caused by compression of the esophagus by the nonaneurysmal tortuous descending aorta (dysphagia aortica). A 69-year-old woman was admitted suffering from dysphagia. Esophagoscopy showed esophageal stenosis caused by pulsatile and extramural compression. Esophagography and aortograms also showed that the nonaneurysmal tortuous descending aorta compressed the esophagus in an anteromedian direction. To avoid the esophageal ulcer and the aortoesophageal fistula, resection of the tortuous aorta and a Dacron graft replacement was performed. After operation compression of the esophagus was released and her complaint improved.

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Cardiac surgery using heparin was performed in a patient in whom AST and ALT had been increased due to continuous drip infusion of heparin sodium. Here, we report postoperative changes in AST and ALT in the patient. The patient was a 59-year-old man with a past medical history of left internal carotid artery constriction and right cerebral infarction. Because of his previous medical history, continuous drip infusion of heparin was initiated upon discontinuation of preoperative antithrombotic agents. AST and ALT increased, but returned to normal levels when heparin was discontinued. Heparin was used to avoid aggravation of the symptoms, and bypass of 3 branches was performed with pulsation. Postoperative respiration and circulatory dynamics were stable, and the courses of AST and ALT were similar to those after general surgery, without abnormally high levels. Although the cause of heparin-induced increases in AST and ALT is unknown, the absence of postoperative increases may have been due to transient use at a high dose and neutralization by protamine.

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A 75-year-old man was referred to our hospital with dyspnea on effort, recurrent attacks of loss of consciousness and abnormal shadow on chest X-ray film. Computed tomographic scan confirmed a 1.5×2.0cm mass with slight spiculation in the right lower lobe (S6) and revealed an ovoid right atrial mass. Transthoracic echocardiography showed that the giant mass which filled most of the right atrium had no mobility. Coronary angiography revealed clusters of new vessels which originated from the atrial branches of the circumflex coronary artery. A T1-weighted MRI scan demonstrated that the mass was isointense relative to the adjacent myocardium. We considered that performing cardiac surgery prior to pulmonary resection, as in a staged procedure, would have advantages in morbidity. We first performed removal of the right atrial tumor which was a 6.8×5.5×4.5cm shiny mass attached to the interatrial septum. Histological examination of the mass confirmed the diagnosis of cardiac myxoma. Three months later, right S⁶ segmentectomy was carried out using thoracoscopy and the tumor was finally diagnosed as squamous cell carcinoma. We have followed the patient for about 10 months after the first operation and there is no evidence of tumor recurrence and no more syncopic attacks.

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A 72-year-old woman complaining of orthopnea was admitted with cardiogenic shock. Her systolic blood pressure was only 66mmHg and electrocardiogram showed high lateral myocardial infarction. Transthoracic echocardiogram showed severe mitral regurgitation and disruption of the anterolateral papillary muscle. After orotracheal intubation and intraaortic balloon pumping (IABP), coronary angiogram was performed and an occlusion of the entrance of circumflex artery (#11) was diagnosed. Percutaneous coronary intervention was done successfully and emergency mitral valve replacement was performed using a St. Jude Medical prosthetic valve preserving the posterior mitral valve leaflet and mitral apparatus. Her postoperative recovery was entirely uneventful and she was followed up as an outpatient. Acute anterolateral papillary muscle rupture is a rare complication of acute myocardial infarction (AMI), although left coronary artery disease is associated with it and immediate recanalization is an important issue to rescue the patient.

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We report a case of emergency operation for ruptured abdominal aortic aneurysm with intraoperative cardiac arrest. The patient was a 71-year-old man with a past history of CABG and total gastrectomy. A transperitoneal approach was used for operation. Intraoperatively, a large retroperitoneal hematoma and intestinal adhesion were found. This large retroperitoneal hematoma increased, followed by cardiac arrest. Immediately left thoracotomy, direct cardiac massage and digital compression to the descending aorta were performed. After aneurysmal opening, an occlusion balloon was inserted in descending aorta. The infrarenal aorta was exposed and clamped. Cardiopulmonary resuscitation was successful. The aneurysm was replaced with a bifurcated artificial vessel and distal anastomosis to the bilateral femoral arteries. There were no signs of cardiac or renal failure in the early postoperative period. The postoperative recovery was successful.

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Cardiovascular surgery in situs inversus totalis (SIT) is unusual. We report a case of coronary artery bypass grafting (CABG) in SIT. A 67-year-old man with unstable angina pectoris was admitted to our hospital. Coronary arteriography demonstrated three-vessel disease in the mirror-image heart. CABG with 4 distal anastomosis was carried out with conventional methods. Careful observation based on complete understanding for preoperative images could minimize operative difficulties caused by mirror-image heart.

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We encountered a case of ascending aorta pseudoaneurysm due to a Freestyle-valve free-wall fistula after a modified Bentall procedure with the button technique. A 60-year-old man with Marfan's syndrome who contracted annuloaortic ectasia presented with the onset of Stanford A type acute aortic dissection 3 years ago. The patient underwent aortic root replacement with a Freestyle-valve and ascending and hemi-arch aortic replacement. Thirty-seven months after this operation the patient was re-operated because of pseudo-ascending aorta aneurysm. The cause of the pseudo-aneurysm was a fistula of the Freestyle-valve free-wall and the left coronary artety (LCA) ostial reconstruction component. The fistula was repaired by direct closure with pledgets. The patient was discharged from the hospital 24 days after the operation.

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Detection of the coronary artery is usually an easy procedure in the coronary artery surgery. However in cases with an intra-muscular and/or intra-fat coronary artery, it requires special skill and experience. Dissection of epicardial adipose tissue and/or muscle along the epicardial groove is a common procedure to reach such coronary artery in conventional CABG (C-CABG). Recently, off-pump CABG (OPCAB) has become a standard operation, and detection of such a coronary artery is difficult under the beating heart. Then conversion to the C-CABG becomes necessary to avoid ventricular rupture. We report a new procedure to easily detect such a coronary artery in OPCAB, using an ultrasonic Fowmeter used in neurosurgery. Because the tip of the probe is small (2mm in diameter) and flexible, its handling is quite similar to that of the micro-blade knife. Furthermore, audiable Doppler flow sound allows detection and dissection of the coronary artery without looking away from the operative field to check the coronary flow. In our case, use of the instrument enabled us to detect the anterior descending branch of the left coronary artery which was very deep in adipose tissue. Therefore, application of this ultrasound instrument is beneficial in OPCAB with an intra-muscular and/or intra-fat coronary artery.

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