Introduction

In this study, we constructed an RRT database solely for patients with sepsis in the ICU. The RRT data stored in this database can be used to determine the association between mortality in sepsis treated without anticoagulation. This study also examines how RRT can be performed safely by determining the relationship between circuit state and RRT circuit life.

Methods

The study period was January 1, 2014 to December 31, 2018. RRT was compared between a non anticoagulant group and an anticoagulant group. The primary endpoint was 90-day mortality. Secondary endpoint was circuit life.

Results

Mortality was higher in the non-anticoagulant group than in the anticoagulant group (64% vs. 52%, P = 0.28), although the difference was not significant. IHD circuit life was significantly different between the groups (P = 0.008), and completion rates were high (82% vs. 92%, P = 0.01). While CRRT circuit life did not differ significantly between the groups (P = 0.47), completion rates were low (29% vs.32%, P = 1).

Conclusions

In this study, we constructed an RRT database in order to analyze epidemiological information about sepsis and RRT implementation conditions in non-anticoagulant therapy.