This study investigated how different treadmill running periods effected bone mechanical strength in ovariectomized mice. Eighty female ICR mice aged 12-weeks-old were used. All mice were divided into 8 groups (n=10) randomly, and had either a sham-operation (n=10) or an ovariectomy (n=70). The SHAM group and one OVX group (NR) were used as non-running control groups, with the remainder comprising the treadmill running groups : the LA (8 m/min), MA (16 m/min), and HA (24 m/min) groups which ran for 12 weeks, and the LB (8 m/min), MB (16 m/min), HB (24 m/min) groups which ran for 6 weeks for 25 min on 5 days/week. After this experiment, maximum loads for the femur and tibia were measured by three-pointed bending test, and the bone mechanical strength of the bones was calculated. Also, the dry bone weight and ash content of the bones were measured. Maximum femur and tibia load and bone mechanical strength were affected by running speed and term significantly. Maximum load and bone mechanical strength of tibia were shown as an interaction. Bone mechanical strength in all running groups was higher than that in the NR group, significantly. This study suggested that treadmill running prevented a reduction of bone mechanical strength, and that treadmill running was most effective in the LA and MA groups (running at low and medium speed and for a long period).

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The Practical Approach for Dysphasia in the Frail Elderly : Special Reference to Insignificant Aspiration and Harmful Aspiration…Shinji TERAMOTO 413

Transcriptional Changes in Skeletal Muscle Cells in response to Unloading Conditions…Takeshi NIKAWA 417

Approaches to Urological Problems…Osamu ISHIZUKA, Osamu NISHIZAWA 422

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The Healthcare Network Management of Acute Phase Hospital and Convalescent Rehabilitation Wards…Masaki ISE 427

The Present State of and Outlook for the Orthopedics Convalescent Rehabilitation Ward…Hitoshi NISHIMURA 433

Is it possible to shorten the Duration of Patient Stays in the Convalescent Rehabilitation Ward?…Hiroaki KOGA 438

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Physical Functioning Exercises to minimize Long-Term Care Insurance Costs…Shuichi P OBUCHI 444

Preventing Falls in the Elderly…Yohei OTAKA 451

The Significance of introducing e-lectures into the Community…Kenji ISHIDA 454

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